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| Type |
Poster Presentation |
| Area |
유기화학 |
| Room No. |
포스터발표장 |
| Time |
4월 20일 (목요일) 11:00~12:30 |
| Code |
ORGN.P-224 |
| Subject |
An Efficient Method for the Amide unit from Alloc-Protected Ester Using DABAL-Me3 |
| Authors |
김희권
전북대학교 의학전문대학원/핵의학교실, Korea |
| Abstract |
Amide is commonly found in many natural compounds and organic compounds. The synthesis of amides from carboxylic acid derivatives is useful transformation. Moreover, direct formation of amides from the protected ester is attractive in organic chemistry areas. Herein, novel synthetic method for the amide from Alloc-protect ester is described. In the novel synthesis, DABAL-Me3 was utilized to treat ester derivatives to produce the corresponding amides. Particularly, novel reaction protocols do not require exclusion of air or moisture, and all transformation to amides from Alloc-protected ester achieved in high yield. This study offers a useful approach for synthesis of a variety of amide. |
| E-mail |
hkkim717@gmail.com |
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119th General Meeting of the KCS