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| Type |
Poster Presentation |
| Area |
유기화학 |
| Room No. |
포스터발표장 |
| Time |
4월 20일 (목요일) 11:00~12:30 |
| Code |
ORGN.P-236 |
| Subject |
Synthesis and evaluation of dimerized novel imaging ligands for prostate cancer |
| Authors |
권영도, 김희권1,*
전북대학교 의과학과, Korea
1전북대학교 의학전문대학원/핵의학교실, Korea
|
| Abstract |
Prostate cancer is one of common cancers which diagnosed in men. Prostate-specific membrane antigen (PSMA) is known as an imaging target for prostate cancers because PSMA is highly upregulated in the primary cancers and metastases. In the present study, we prepared novel dimerized PSMA inhibitors containing urea unit. Also, the ligands were attached with an imaging agent such as cyanine dye in order to improve ability to detect prostate tumor. Biological evaluations suggest that novel dimerized inhibitors were more potential agents applicable for diagnosis of prostate cancer. |
| E-mail |
gskydgo@gmail.com |
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119th General Meeting of the KCS