119th General Meeting of the KCS

Type Poster Presentation
Area 유기화학
Room No. 포스터발표장
Time 4월 20일 (목요일) 11:00~12:30
Code ORGN.P-240
Subject An Efficient Amidation of Aldehyde Using Bromo group at Room Temperature
Authors 김희권
전북대학교 의학전문대학원/핵의학교실, Korea
Abstract Amide unit is commonly found in a lot of biopharmaceuticals, natural compounds, and polymer. The Amide unit has been utilized to a variety of fields such as plastics, dyes, pharmaceuticals synthesis. The amidation of aldehyde is one of efficient and direct methods for the preparation of amide bonds. However, most of synthetic methods have used harsh reaction condition. Herein, novel and mild synthetic method for the amidation of aldehyde is described. In the novel protocol, aromatic and aliphatic aldehydes were treated with bromo compound for activating aldehydes, and were readily converted the corresponding amides with high yields at room temperature.
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