|
Type |
Poster Presentation |
Area |
유기화학 |
Room No. |
포스터발표장 |
Time |
4월 20일 (목요일) 11:00~12:30 |
Code |
ORGN.P-240 |
Subject |
An Efficient Amidation of Aldehyde Using Bromo group at Room Temperature |
Authors |
김희권 전북대학교 의학전문대학원/핵의학교실, Korea |
Abstract |
Amide unit is commonly found in a lot of biopharmaceuticals, natural compounds, and polymer. The Amide unit has been utilized to a variety of fields such as plastics, dyes, pharmaceuticals synthesis. The amidation of aldehyde is one of efficient and direct methods for the preparation of amide bonds. However, most of synthetic methods have used harsh reaction condition. Herein, novel and mild synthetic method for the amidation of aldehyde is described. In the novel protocol, aromatic and aliphatic aldehydes were treated with bromo compound for activating aldehydes, and were readily converted the corresponding amides with high yields at room temperature. |
E-mail |
hkkim717@gmail.com |
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