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| Type |
Poster Presentation |
| Area |
유기화학 |
| Room No. |
포스터발표장 |
| Time |
4월 20일 (목요일) 11:00~12:30 |
| Code |
ORGN.P-242 |
| Subject |
Tau tangle-specific Near-Infrared Fluorophores |
| Authors |
서진호, 박근영, 구세영, 정태호, 김수빈, 김종승*
고려대학교 화학과, Korea
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| Abstract |
Tau proteins are important in stabilizing microtubules by electrostatic attraction.
Tau proteins are expressed in the neurons of adults, ranging from 352 to 441 amino acids in length.
By hyper phosphorylation, tau proteins disassemble from microtubules and self-aggregate.
It can be accumulated, resulting Nero Fibrillary Tangle (NFT) in the human brain. This NFT is the main cause of Alzheimer disease by interrupting neurons interaction. Detection of Tau tangle is essential in understanding and detecting Alzheimer disease.
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| E-mail |
scour13@naver.com |
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119th General Meeting of the KCS