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| Type |
Oral Presentation |
| Area |
Oral Presentations of Young Scholars in Organic Division |
| Room No. |
302호 |
| Time |
THU 09:15-: |
| Code |
ORGN.O-2 |
| Subject |
Development of Paper-Based Colorimetric Sensor System for the High-Throughput Screening of Ir-catalyzed C-H Borylation |
| Authors |
김한성, 엄민식1, 한민수1,*, 이선우*
전남대학교 화학과, Korea
1GIST 화학과, Korea
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| Abstract |
A paper-based colorimetric sensor system (PBCSS) was developed to analyze the amount of bis(pinacolato)diboron (B2Pin2) and applied as a high-throughput screening protocol in Ir-catalyzed C-H borylation. First, ninety-six ligands were screened for the borylation of benzene, and then twelve of them were selected and tested for five substrates. These reaction mixtures were spotted in the PBCSS, showing a blue-violet color. The value of the gray scale of each reaction was obtained from these colored spots and converted to the extent of conversion of B2Pin2. The extents of conversion of B2Pin2 obtained from the PBCSS showed good correlation with those obtained from gas chromatography analysis. In addition, the modified conversion using blank data showed good correlation with the yield of products.
Acknowledgments
This research was supported by a National Research Foundation of Korea (NRF) grant provided by the Korean government (MSIP) (NRF-2014R1A2A1A11050018, NRF-2015R1A4A1041036) |
| E-mail |
hansung26@gmail.com |
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119th General Meeting of the KCS