119th General Meeting of the KCS

Type Poster Presentation
Area 전기화학
Room No. 포스터발표장
Time 4월 21일 (금요일) 13:00~14:30
Code ELEC.P-518
Subject Fabrication of a Dual Microsensor for Simultaneous Measurements of Carbon Monoxide and Potassium Ion
Authors 우주원, 이영미*
이화여자대학교 화학나노과학과, Korea
Abstract Carbon monoxide (CO) and potassium ion (K+) are significantly related to vasodilation and neurotransmission in physiological systems. CO plays a role as a vasodilator through the activation of soluble guanylyl cyclase (sGC), generating guanosine 3’,5’-cyclic monophosphate (cGMP) which leads to K+ efflux. In addition, CO inhibits apoptosis aroused by K+ channel existing in neuron cells. In this presentation, the development of a dual amperometric microsensor for simultaneous measurements of CO and K+ is demonstrated. A working electrode of the sensor is a dual disk electrode having platinum (Pt) and silver (Ag) microdisks (diameter of both disks, 76 μm). Both Pt and Ag microdisks are electrochemically etched to form dented micropores. Pt micropore is filled with porous bimetallic layers electrodeposited sequentially. Then, the electrode surface is modified with electropolymerized polymer and CO selective membrane for the selectivity to CO over general biological interfering species. Ag micropore is chloridated with FeClH3 to form AgCl, followed by silanization with trimethylchlorosilane (TMCS), and then covered with K+ selective membrane. The sensitivity and selectivity of the dual sensor are experimentally verified for possible biological applications. This research was supported by Basic Science Research Program through the National Research Foundation of Korea (NRF) funded by the Ministry of Science, ICT& Future Planning (2014R1A2A2A05003769).
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