119th General Meeting of the KCS

Type Poster Presentation
Area 생명화학
Room No. 포스터발표장
Time 4월 21일 (금요일) 13:00~14:30
Code BIO.P-293
Subject Studies on distinguishment of various influenza virus subtypes by counter systematic evolution of ligands by exponential enrichment
Authors 이태균, 정용주*
국민대학교 생명나노화학과, Korea
Abstract Flu is caused by infection from influenza virus and brings symptoms like cold. Influenza virus contained single-stranded RNA. If this disease is transmitted to human by poultry, the situation becomes serious. There are many subtypes in influenza virus depending on the kinds of hemagglutinin (HA) and neuraminidase (NA). HA is a surface protein of influenza virus, and this is involved in the viral infection by binding the sialic acid of the host cell. All subtypes of influenza virus have different types of HA. So we have tried to find molecular probes that specifically bind to each different HA for diagnosis of the various influenza virus. To find the probes, we have applied the counter systematic evolution of ligands by exponential enrichment (Counter-SELEX) method. Then, we measured the binding affinity of the probes by enzyme-linked immunosorbent assay. We expect the probes will be helpful to distinguish the various types of HA and diagnose influenza virus.
E-mail haroun90@naver.com