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|
| Type |
Poster Presentation |
| Area |
생명화학 |
| Room No. |
포스터발표장 |
| Time |
4월 21일 (금요일) 13:00~14:30 |
| Code |
BIO.P-295 |
| Subject |
Characterization of Middle East Respiratory Syndrome Coronavirus Helicase |
| Authors |
표소희, 정용주*
국민대학교 생명나노화학과, Korea
|
| Abstract |
An infectious respiratory disease, Middle East Respiratory Syndrome (MERS), is caused by a modified coronavirus. MERS coronavirus is a (+) single stranded RNA virus. Of the several non-structural proteins produced from the virus, NTPase/helicase plays an important role in viral replication. Helicases are motor proteins that separate double-stranded nucleic acids using energy generated from ATP hydrolysis. In the present study, we purified a recombinant MERS coronavirus helicase and measured ATP hydrolysis rates in the presence of various kinds of nucleic acids. In addition, basic kinetic parameters were also obtained. |
| E-mail |
pyosooo@hanmail.net |
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119th General Meeting of the KCS