119th General Meeting of the KCS

Type Poster Presentation
Area 생명화학
Room No. 포스터발표장
Time 4월 21일 (금요일) 13:00~14:30
Code BIO.P-314
Subject Studying effect of ECM on mechanical properties of artificial cells by micropipette aspiration
Authors 김민영, 신관우1,*
서강대학교 화학, Korea
1서강대학교 화학과 및 바이오융합과정, Korea
Abstract Mechanical properties of cells and factor which can change properties have been studied in many previous papers. The extracellular matrix (ECM) has important roles in regulating the development, function and homeostasis of all eukaryotic cells. GUV which contain PS lipid can be coated with ECM because of its negative charge. This GUV can be measured by micropipette aspiration. Micropipette aspiration is one of the methods for measuring mechanical properties of cell and vesicle membrane. Area expansion modulus can be calculated. By suction of membrane into micropipette, we can get response or modulus data about mechanical loading on GUV which is coated with ECM. Then, we observed the effect of ECM to mechanical properties of cells.
E-mail gamin993@hanmail.net