|
Type |
Poster Presentation |
Area |
의약화학 |
Room No. |
포스터발표장 |
Time |
4월 20일 (목요일) 11:00~12:30 |
Code |
MEDI.P-456 |
Subject |
Recent biologically-oriented applications of corroles |
Authors |
윤새미, 선경표, 하용황1,* 중원대학교 의약화학과, Korea 1중원대학교 의약바이오학과, Korea |
Abstract |
Various corrole compounds, which have very similar core structure with porphyrin, have been attracted many interests with respect to synthetic strategies and biological applications. Although photophysical properties of corroles are similar porphyrin molecules, biological characteristics exhibit more improved applicability for molecular imaging, detection and degradation of tumors, DNA sensors, catalytic degradation of reactive nitrogen species (RNS), and generation of singlet oxygen as photosensitizers. Herein, we reviewed photophysical properties, and examples of biological applications of corroles and discussed the structural characteristics of each application. We expected this review can be a basic study for corrole applications in biological and therapeutic studies. |
E-mail |
hyh3455@jwu.ac.kr |
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