119th General Meeting of the KCS

Type Oral Presentation
Area Bioconjugation
Room No. 403호
Time THU 09:30-:
Code BIO.O-4
Subject Current status and technological trends in the development of antibody-drug conjugates
Authors 이선배
(주)알테오젠 R&D center, Korea
Abstract Antibody-drug conjugates (ADCs) elicit cancer-cell specific cytotoxicity by delivering highly potent drugs selectively to antigen-expressing tumor cells. Various parameters must be considered in designing optimal ADC construct, such as optimal drug-to-antibody ratio, conjugation method, cytotoxic payloads, and antigen specific mAb. Recent advance and technological trends in this field will be presented.
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