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Type |
Oral Presentation |
Area |
Bioconjugation |
Room No. |
403호 |
Time |
THU 09:30-: |
Code |
BIO.O-4 |
Subject |
Current status and technological trends in the development of antibody-drug conjugates |
Authors |
이선배 (주)알테오젠 R&D center, Korea |
Abstract |
Antibody-drug conjugates (ADCs) elicit cancer-cell specific cytotoxicity by delivering highly potent drugs selectively to antigen-expressing tumor cells. Various parameters must be considered in designing optimal ADC construct, such as optimal drug-to-antibody ratio, conjugation method, cytotoxic payloads, and antigen specific mAb. Recent advance and technological trends in this field will be presented. |
E-mail |
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