120th General Meeting of the KCS

Type Symposium
Area [Tutorial] NMR Applications in Chemistry
Room No. Room 208+209+210
Time WED 15:00-:
Code KCS1-1
Subject Structure Determination of Small Organic Compounds by Solution NMR Method
Authors Jung-Rae Rho
Kunsan National University, Korea
Abstract Solution Nuclear Magnetic Resonance (NMR) is an excellent tool for determining the structures of small organic compounds like natural products at the level of individual atoms. Instead of a direct picture or image of the molecule, the structure can be interpreted by a series of NMR spectra which provide the connectivity between an atom and its neghboring atoms in the molecule. In many cases 1D NMR (1H and 13C) and 2D NMR (COSY, TOCSY, HSQC, and HMBC) experiments routinely enabled us to determine the planar structure of a molecule less than 1000 Da and also NOESY/ROESY experiment established the relative configurations within the rigid part of the molecule. In this presentation, the nature of these experiments will be dealt in more detail, and all these experiments will be applied to determine the structure of a natural product as an example.
E-mail jrrho@kunsan.ac.kr