Coordination-driven self-assembly process used for the synthesis of 2D and 3D molecular architectures has been of great importance owing to their application in catalysis, drug-delivery and encapsulation. Cobalt sandwich based tetrapodal ligand has unique properties to construct face-based conformational isomers by directing the cyclopentadiene unit inside or outside of the cage. Herein, we describe the synthesis of supramolecular cages, which possess cubic and trigonal prism geometry and subsequently use them for the encapsulation of various guest molecules.