120th General Meeting of the KCS

Type Poster Presentation
Area Organic Chemistry
Room No. Exhibition Hall 2+3
Time 10월 20일 (금요일) 13:00~14:30
Code ORGN.P-282
Subject Facile Synthesis of Diphenylmethyl esters using 2-Diphenylmethoxy-1-methylpyridinium Triflate under mild condition
Authors Minh Thanh La, Hee-Kwon Kim1,*
Department of Medical Science, Medical School, Chonbuk National University, Korea
1Department of Nuclear Medicine, Medical School, Chonbuk National University, Korea
Abstract Protection and deprotection of esters are one of the most important methodologies in organic synthesis. Diphenylmethyl group has been widely used as a protecting group for carboxylic acids. Here, Novel practical method for the conversion of carboxylic acids to diphenylmethyl (DPM) esters is described. DMP esters were synthesized through the reacction with 2-diphenylmethoxy-1-methylpyridinium triflate intermediates which were formed in situ from the treatment of MeOTf and 2- diphenylmethoxy-1-methylpyridinium. Using this reaction protocol, various diphenylmethyl (DPM) esters were prepared with high yields under mild condition. This effective method is highly effective method for the synthesis of DMP esters, and offers a promising approach for facile esterification of a variety of carboxylic acids.
E-mail lmthanh1912@gmail.com