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|
| Type |
Poster Presentation |
| Area |
Analytical Chemistry |
| Room No. |
Exhibition Hall 2+3 |
| Time |
10월 19일 (목요일) 11:00~12:30 |
| Code |
ANAL.P-184 |
| Subject |
Optimization of sample preparation for the identification of GB-tyrosine in rat plasma exposure to GB |
| Authors |
JIHYUN KWON, Yong Gwan Byun, Yong Han Lee*
Agency for Defense Development, Korea
|
| Abstract |
The identification of the chemical warfare agent, isopropyl methlyphosphonofluoridate (sarin, GB) in plasma has been studied using liquid chromatography-tandem mass spectromety (LC-MS/MS). However, systematic study of sample preparation for LC-MS/MS was not done a lot. Therefore, the sample preparation for the identification of GB-tyrosine in rat plasma was studied. Also, the lowest detection concentration of GB-tyrosine for LC-MS/MS was reported using the optimized sample preparation. The optimized sample preparation will be employed to study other types of nerve agent in plasma. |
| E-mail |
jhkwon8@add.re.kr |
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120th General Meeting of the KCS