120th General Meeting of the KCS

Type Oral Presentation
Area Oral Presentation of Young Material Chemists
Room No. Room 214
Time THU 09:40-:
Code MAT.O-5
Subject Gyromagnetic Plasmonic Nanorods for Shear Force-Induced Biosensing
Authors Insub Jung, Sungho Park1,*
Department of Energy Science, Sungkyunkwan University, Korea
1Department of Chemistry, Sungkyunkwan University, Korea
Abstract Biosensing based on the localized surface plasmon resonance of metallic nanostructures is a powerful tool for the detection of target species. To increase sensitivity, the systematic synthesis of complex nanostructures along with the design of a sensing platform with a rational configuration is critically important. However, most LSPR-based sensors operate in a passive and static way, hindering further improvements to their sensitivity and detection time. Herein, we report an unprecedented active and dynamic sensing platform based on a LSPR configuration that is modulated by using an external magnetic field. Electrochemically-synthesized Au/Fe/Au nanorods exhibited plasmonically-active behavior through plasmonic coupling, and the middle ferromagnetic Fe block responded to a magnetic impetus, allowing the nanorods to be modulated. The shear force variation induced by the specific binding events between antigens and antibodies on the nanorod surface is used to enhance the sensitivity of detection of antigens in the plasmonics-based sensor application. As a proof-of-concept, influenza A virus (HA1) was used as a target protein. This conceptual sensing method provides a new platform for active plasmonic-magnetic biosensing.
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