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| Type |
Poster Presentation |
| Area |
Medicinal Chemistry |
| Room No. |
Exhibition Hall 2+3 |
| Time |
10월 19일 (목요일) 11:00~12:30 |
| Code |
MEDI.P-341 |
| Subject |
Tryptamine Derivatives for Novel Cholinesterase Inhibitors |
| Authors |
Cheolmin Jeon*, Jeong Ho Park1,*, haneul lee, Yujung Kang
Department of Chemical & Biological Engineering, Hanbat National University, Korea
1Division of Applied Chemistry & Biological Enginee, Hanbat National University, Korea
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| Abstract |
Cholinesterase inhibitors are on market to treat Alzheimer’s disease (AD). Development of novel Alzheimer's drugs based on the cholinergic theory are still one of the best targets for AD. We have been researching to find out new candidate compounds as cholinesterase inhibitors. In this study, a series of tryptamine derivatives were synthesized and their in vitro cholinesterase [acetylcholinesterase (AChE) and butyrylcholinesterase (BuChE)] inhibitory activities were evaluated. |
| E-mail |
cjfals2970@naver.com |
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120th General Meeting of the KCS