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| Type |
Poster Presentation |
| Area |
Life Chemistry |
| Room No. |
Exhibition Hall 2+3 |
| Time |
10월 19일 (목요일) 11:00~12:30 |
| Code |
BIO.P-270 |
| Subject |
Delivery of Fibronectin into fibroblast via Small Unilamellar Vesicles for wound healing
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| Authors |
Mary Chuong, Minyoung Kim1, Kwanwoo Shin2,*
Chemistry, student, Korea
1Chemistry, Sogang University, Korea
2Department of Chemistry, Sogang University, Korea
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| Abstract |
Fibronectin(FN) is a key component of extracellular matrix, playing a primary role in tissue repair and cell growth. It exists in two forms: plasma fibronectin and cellular fibronectin. In this study, plasma fibronectin was used and coated on negatively charged lipid vesicles, known as small unilamellar vesicles(SUVs). Our goal was to observe the effect of
FN-SUV on cell growth and wound healing. SUVs were fabricated and incubated with FN at 37ºC for 12hr. Then the complex of FN-SUVs was delivered into fibroblast. The observation of cell growth with and without the presence of FN-SUV was conducted in every 12hr. The results show that the rate of cell growth is faster with the treatment of FN-SUV comparing to without the treatment. Additionally, this FN-SUV also assists wound healing.
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| E-mail |
marychuong05@gmail.com |
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120th General Meeting of the KCS