|
Type |
Oral Presentation |
Area |
Oral Presentation of Young Analytical Chemists II |
Room No. |
Room C308+C309 |
Time |
FRI 09:58-: |
Code |
ANAL2.O-22 |
Subject |
Investigation of sample preparation and analysis methods for profiling organic chemicals and metals in teeth |
Authors |
Eunji Seo, Sangwon Cha* Department of Chemistry, Hankuk University of Foreign Studies, Korea |
Abstract |
Recently, due to its specific structure and growth pattern, deciduous teeth have been proposed to be retrospective temporal biomarkers for exposomics researches which try to assess comprehensively environmental exposures from the fetal period onwards. However, sample preparation and analysis steps for teeth samples have not been explored extensively and need to be standardized. In this study, we investigated various sample preparation procedures and mass spectrometric methods for profiling organics and metals present in teeth samples. In order to evaluate sample preparation procedures including sampling, pulverization, incubation, and extraction, we employed paper spray ionization (PSI) mass spectrometry (MS), paper cone spray ionization (PCSI) MS, and MALDI MS. In addition, we tested various LC/MS methods for organic chemical analysis and laser ablation-based elemental mapping methods for spatially resolved metal analysis. |
E-mail |
dmswl12321@naver.com |
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