120th General Meeting of the KCS

Type Poster Presentation
Area Electrochemistry
Room No. Exhibition Hall 2+3
Time 10월 20일 (금요일) 13:00~14:30
Code ELEC.P-495
Subject Separation analysis of neurotransmitters using a AC field applied-microfluidic channel with an amperometric sensor
Authors mohammad mozammal hossain, Yoon Bo Shim*
Department of Chemistry, Pusan National University, Korea
Abstract A separation analysis of various neurotransmitters in human urine and blood samples was performed using AC field applied microfluidic channel device, attached with an external amperometric sensor. The sensor was fabricated by electropolymerization of poly (2,2´:5´,5″-terthiophene-3´-p-benzoic acid) (pTBA) and porous carbon (PC) layer onto the screen printed electrode (SPCE), followed by covalent immobilization of a redox active mediator. The sensor probe material was characterized employing electrochemical impedance spectroscopy (EIS), X-ray photoelectron spectroscopy (XPS) and various other electrochemical methods. The experimental parameters affecting the analytical performances for dopamine, norepinephrine, epinephrine, serotonin, 3, 4-dihydroxy-l-phenylalanine, 5-hydroxyindoleacetic acid, and 5-hydroxytryptophan are optimized. The reliability of the analytical method was demonstrated by determining seven neurotransmitters (DA, NE, EP, 5-HT, L-dopa, 5-HIAA and 5-HTP) in human urine and blood samples.
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