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| Type |
Poster Presentation |
| Area |
Electrochemistry |
| Room No. |
Exhibition Hall 2+3 |
| Time |
10월 20일 (금요일) 13:00~14:30 |
| Code |
ELEC.P-498 |
| Subject |
A Chemically Modified Electrode with Polyaniline Derivatives: Experimental and Theoretical Mechanism Studies |
| Authors |
Heesu Kim, Rakwoo Chang, Jae Ho Shin*
Department of Chemistry, Kwangwoon University, Korea
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| Abstract |
Carbon monoxide (CO) which is naturally produced by the action of heme oxygenase in the human body, plays diverse physiological roles as a signaling molecule. Abnormalities in its metabolism have been linked to a variety of diseases, including hypertension, neurodegeneration, heart failure, and inflammation. Therefore, the reliable detection of CO in vivo is essential to elucidate its numerous biological functions. However, the electrochemical measurement of CO has been challenging due to its low concentration, rapid diffusion, and severe interference from other electrochemically active species (e.g., nitric oxide, nitrite, ascorbic acid, and uric acid). Indeed, the utility of a tin (Sn)-deposited Pt electrode (previously known as an amperometric CO sensor) has been hindered by significant interference from nitric oxide (NO). The elimination of NO interference in the CO sensor development is one of the important factors, because CO’s biological functions are closely related to NO’s ones. Herein we report on a novel amperometric CO sensor with superior sensitivity and selectivity (especially over NO) via use of aniline derivatives as a sensing membrane. The films of aniline or its derivatives are deposited on a Pt electrode by electropolymerization (i.e., cyclic voltammetry). The sensing mechanism and the effect of electropolymerization conditions (e.g., scan rate, number of scan cycles, and types of anions doped during polymerization) will be discussed. The effect of dopant anions (e.g., hydrogen sulfate, dodecyl sulfate, and tetraborate) on sensor performance will be also evaluated. Furthermore, to investigate the substituent effect of aniline derivatives on sensor performance at the atomic level, the density functional theory (DFT) studies have been carried out with a series of aniline derivatives ortho-substituted with electron donating (e.g., methyl and ethyl) or electron withdrawing (e.g., fluoro, chloro, bromo, carboxylic, trifluoromethyl, and sulfonic) groups. The calculations are performed at unrestricted UB3LYP/6-31G(d) using the Gaussian 09 package with the dimer model of aniline derivatives. |
| E-mail |
heesu9292@naver.com |
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120th General Meeting of the KCS