120th General Meeting of the KCS

Type Symposium
Area [IBS Symposium] Developing New Catalytic Organic Reactions and Investigating Their Applications
Room No. Room 211+212+213
Time WED 16:20-:
Code KCS3-4
Subject Development of Bifunctional N-Heterocyclic Carbene Ligands
Authors Sukwon Hong
Department of Chemistry, Gwangju Institute of Science and Technology, Korea
Abstract Cooperative catalysis enabling simultaneous activation of both an electrophile and a nucleophile has emerged as a powerful strategy in organic synthesis. We envision that imidazo[1,5-a]pyridine-derived N-heterocyclic carbene (ImPy) ligands will provide a convenient framework where a various functional group can be easily implemented to make bifunctional N-heterocyclic carbene ligands. Several transition metal complexes containing imidazopyridinylidene carbene (ImPy) ligands have been prepared. The ImPy-Cu(I) complexes efficiently catalyzed the direct C-H carboxylation of benzoxazole with CO2. ImPy-Pd catalysts exhibited good reactivity in Buchwald-Hartwig amination reactions. Current progress on design of new bifunctional ImPy transition metal catalysts will be discussed in details in the presentation.
E-mail shong@gist.ac.kr