120th General Meeting of the KCS

Type Oral Presentation
Area Oral Presentation of Young Analytical Chemists I
Room No. Room C311+C312
Time THU 10:51-:
Code ANAL1.O-46
Subject Classification of glycoproteins by pattern identification in traditional Korean medicine (TKM) in human plasma from lung cancer patients
Authors Jihoon Shin, jinwook lee, Min-gyu youn, miseon jeong, Jeonghoon Kang, Wonryeon Cho*
Department of Bio-nanochemistry, Wonkwang University, Korea
Abstract Patients have difficulties in seeking treatments based on T0raditional Korean Medicine (TKM) because of the lack of standardized diagnosis. This study is a preliminary research for patient-specific TKM aiming at the discovery of biomarker for lung cancer diagnosis using the proteomics approach. Glycoproteins are well-known to be associated with diseases (especially cancers) and can be used as biomarkers for corresponding diseases. Six groups (EX, ES, EN, RX, RS and RN) from Lung cancer patients are independently analyzed through glycoproteomics approach based on the pattern identification in TKM. This lead to (1) establish the standardized methodology with proteomics for the pattern identification of lung cancers under the framework of TKM; (2) discover lung cancer biomarkers using TKM and then develop in vitro diagnostic kits for lung cancers that optimize these biomarkers to establish patient-specific TKM for further treatment.
E-mail wcho@wku.ac.kr