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| Type |
Oral Presentation |
| Area |
Oral Presentation of Young Analytical Chemists II |
| Room No. |
Room C308+C309 |
| Time |
FRI 10:27-: |
| Code |
ANAL2.O-34 |
| Subject |
Application of gradient generating microdroplet-based chips for rapid and sensitive bioanalysis
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| Authors |
Jinhyeok Jeon, JAEBUM CHOO*
Department of Bionano Technology, Hanyang University, Korea
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| Abstract |
Microfluidic technology have recently emerged as an efficient tool for the study of various chemical or biological reactions. Recently, we reported that high-throughput chemical or biological reactions could be performed in a continuous flow microfluidic channel with an automatic manner. However, there is a “memory effect” problem in the continuous flow system. Samples in the continuous stream could be stacked in the wall of a microfluidic channel, and they may occur unwanted flow hindrance. To resolve this problem, we recently developed a novel gradient microdroplet system. In this system, the sample stacking problem can be solved since two-phase liquid/liquid segmented flow reduces the memory effect. A serial dilution of reagent can be achieved in a stepwise manner using microfluidic concentration gradient generators. Then, desired concentrations of a reagent were sequentially trapped by a small volume of droplets to prevent the sample stacking. We believe that this microdroplet system will be of significant utility in monitoring chemical and biological effects for various concentrations of a reagent. |
| E-mail |
jeonjh1004@naver.com |
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120th General Meeting of the KCS