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|
| Type |
Poster Presentation |
| Area |
Organic Chemistry |
| Room No. |
Event Hall |
| Time |
4월 19일 (목요일) 11:00~12:30 |
| Code |
ORGN.P-332 |
| Subject |
An efficient synthesis of nitrogen containing heterocyclic resveratrol analogs |
| Authors |
Lee Seul Park, Jeong Tae Lee*
Department of Chemistry and Institute of Applied Chemistry, Hallym University, Korea
|
| Abstract |
Nitrogen containing heterocyclic compounds are important components of various biologically active compounds. A series of resveratrol analogs were synthesized to enhance the antioxidant activity of resveratrol (3,5,4’-trans-trihydroxystilbene), a well-known natural product with strong antioxidant activity. We have synthesized naphthalene, quinoline, isoquinoline, quinoxaline, and quinazoline scaffolds containing resveratrol core by Wittig-Horner reaction or metal-catalyzed reactions as key steps. The antioxidant activity of these compounds has been measured by the ABTS assay and we anticipate some of the compounds may exhibit better activity than that of the lead compound, resveratrol. |
| E-mail |
hellobong3@nate.com |
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121st General Meeting of the KCS