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| Type |
Poster Presentation |
| Area |
Physical Chemistry |
| Room No. |
Event Hall |
| Time |
4월 20일 (금요일) 11:00~12:30 |
| Code |
PHYS.P-78 |
| Subject |
Various sizes of polyacrylic acid (PAA) coating ultrasmall Gd2O3 nanoparticles and the effect on the water proton relaxivities of different ligand |
| Authors |
Xu Miao, Gang Ho Lee1,*
Department of Chemistry, Kyungpook National University, China
1Department of Chemistry, Kyungpook National University, Korea
|
| Abstract |
Highly water soluble and biocompatible nanoparticles with low toxicity and diversification of imaging modality are widely used in biomedical application. To make stable nanoparticles with less toxicity, it is necessary to coat nanoparticles with hydrophilic and bio-compatible ligands. Here, we synthesized ultrasmall Gd2O3 nanoparticles coated with polyacrylic acids (PAAs) of different molecular weights. The PAA-size-dependent relaxometric properties of the thus obtained composites were investigated. They are characterized with FT-IR, XRD, TGA, TEM, Toxicity test, and MRI instrument. In this study it is shown that all samples with good biocompatibility and the r1 and r1 values decreased with increasing PAA size. The magnetic property and their potential as T1 MRI contrast agent. |
| E-mail |
kitty0927@live.cn |
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121st General Meeting of the KCS