121st General Meeting of the KCS

Type Poster Presentation
Area Physical Chemistry
Room No. Event Hall
Time 4월 20일 (금요일) 11:00~12:30
Code PHYS.P-80
Subject Poly acrylic acid (PAA ~1800) Coated Lanthanide oxide Nanoparticles for Magnetic Resonance Imaging Contrast Agent
Authors SHANTI MARASINI, Gang Ho Lee1,*
Department of Chemistry, Kyungpook National University, Nepal
1Department of Chemistry, Kyungpook National University, Korea
Abstract Multifunctional water soluble polymer as a coating ligand has played a crucial role in synthesis of magnetic nanoparticles. These polymers render magnetic nanoparticles more stable, water soluble and uniform which makes it easier for post synthesis modification and functionalization for bio-applications. Here, we synthesized ultrasmall Dysprosium oxide and Holmium oxide nanoparticles coated with water soluble and biocompatible poly acrylic acid using polyol method. Nanoparticles were characterized by measuring their particle diameter, hydrodynamic diameter, surface coating, r1 and r2 values, map images, and in vitro cellular toxicity using different characterization techniques. In this study, the magnetic property and their potential as T2 MRI contrast agent has been studied.
E-mail shantimarasini.sm@gmail.com