|
|
| Type |
Poster Presentation |
| Area |
Medicinal Chemistry |
| Room No. |
Event Hall |
| Time |
4월 19일 (목요일) 11:00~12:30 |
| Code |
MEDI.P-579 |
| Subject |
Advanced immunosensor for prostate cancer using later flow assay |
| Authors |
kyoung yeol park, Tae Jung Park*
Department of Chemistry, Chung-Ang University, Korea
|
| Abstract |
Prostate cancer is a malignant tumor in the prostate, where is a gland in the male reproductive system. It is the second most common type of cancer and fifth leading casue of cancer-related death in male. In 2017, about 160,000 new cases of prostate cancer were reported and roughly 26,000 patients died in America. The most general way to diagnose prostate cancer is to screen specific antigen from the tumorous tissues such as prostate-specifie antigen (PSA) or digital rectal exam (DRE) with advantages of being much easier, less expensive and less invasive compared to biopsy. Especially, PSA test can be considered useful in the way that it can find the caner in people before they have symptoms with relatively lower expenses. People have been diagnosed as having a high chance of prostate cancer when PSA level in blood exceeds 4 ng/ml. However, this test usually gives false-positive or false-negative results. According to National Cancer Institute, only about 25% of men with an elevated PSA level in range of 4~10 ng/ml turned out to have prostate cancer. The United States Preventive Services Task Force and the American Cancer Society recommends against PSA test due to the risk of overdiagnosis and overtreatment as a result. Therefore, we are developing more accurte immunoassay kit using not only PSA but also the leading biomarkers of prostate cancer. This immunoassay method using a lateral flow assay will be used as a new screening method for more accurate prostate cancer diagnosis in advance. |
| E-mail |
ruddufcjstk0522@gmail.com |
|
121st General Meeting of the KCS