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| Type |
Poster Presentation |
| Area |
Organic Chemistry |
| Room No. |
Event Hall |
| Time |
4월 19일 (목요일) 11:00~12:30 |
| Code |
ORGN.P-336 |
| Subject |
Pd-catalyzed Enatioselective Suzuki-Miyaura Cross-Coupling Reaction of Silyl-Substituted 1,1-Diborylmethanes with Aryl Iodides |
| Authors |
junghoon Kim, Seung Hwan Cho*
Department of Chemistry, Pohang University of Science and Technology, Korea
|
| Abstract |
Organodimetallic reagents which have two metal moieties have become useful building blocks for highly functionalized molecules. Among those reagents, 1,1-borylsilylalkanes are considered as one of the most powerful reagents, due to their stability and versatility. However, despite the progress of studies on the synthesis of 1,1-borylsilylalkanes over a long period of time, most of them are limited to the synthesis of racemic compounds. Currently, only few methods are available to synthesize the enantioenriched compounds. Herein, we report a novel reaction to synthesize chiral 1,1-borylsilylalkanes through coupling reaction with aryl halides in the presence of Pd-catalyst using silylated 1,1-diborylmethanes. |
| E-mail |
kjh0711@postech.ac.kr |
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121st General Meeting of the KCS