The tetraphenylethylene (TPE)-based building block was synthesized. We investigated the self-assembled behavior in THF with mechanical control. The self-assembled TPE showed the weak greenish emission without stirring. In contrast, the self-assembled TPE revealed the strong blue emission with fast stirring. The blue fluorescence intensity of TPE was dependent to the stirring rate. Furthermore, the positive CD signal of TPE derivative enhanced gradually with stirring rate, indicates that TPE derivative molecules were orientated to the left-handed helicity. Also AFM image of TPE building block showed helical aggregators. In this conference, we will present the self-assembled behavior of TPE derivative in detail.