121st General Meeting of the KCS

Type Poster Presentation
Area Organic Chemistry
Room No. Event Hall
Time 4월 19일 (목요일) 11:00~12:30
Code ORGN.P-355
Subject Adaptation of High Throughput Screening in Novel Antioxidant Discovery
Authors gaosheng Shi, Sangho KOO1,*
Department of Energy Science and Technology, Myungji University, China
1Department of Chemistry, Myungji University, Korea
Abstract High throughput screening, which is widely applied in biochemical science, is one of the new and effective approaches to the drug discovery. According to the previous reports, the whole process of high throughput has been implemented to the automation of robots, detectors and software. It could examine 100,000 compounds per day. Recently we applied this method to screening the antioxidant activity of novel carotenoids, adding the statistics of the algorithm (cluster analysis and principal component analysis), which can establish a new model to analyze the structure-activity relationship of carotenoid derivatives and screen target antioxidant in a short time.
E-mail kooslaboffice@gmail.com