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| Type |
Poster Presentation |
| Area |
Organic Chemistry |
| Room No. |
Event Hall |
| Time |
4월 19일 (목요일) 11:00~12:30 |
| Code |
ORGN.P-356 |
| Subject |
The application of Mn(Ⅲ)/Co(Ⅱ) Catalyzed Oxidative Deacetylation In Biologically Important Heterocyclic Compounds Synthesis |
| Authors |
Hui Jin, Sangho KOO1,*
Department of Energy Science and Technology, Myungji University, China
1Department of Chemistry, Myungji University, Korea
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| Abstract |
The conjugate addition of 1,3-dicarbonyl compounds to α, β-unsaturated carbonyl compounds produce 1,5-dicarbonyl compounds, which are ideally suited for the Mn(III)/Co(II)-catalyzed oxidative deacetylation to form 1,4-dicarbonyl compounds.A new type of hetero-cyclization directed by a 1,4-dicarbonyl compound has been developed. Based on the above oxidation,a high yield of oxidative deacetylation was gained under the condition of 5 mol% Mn(AcO)3 and 2 mol% CoCl2.
One pot syntheses of furan, thiophene, and pyrrole were accomplished by using Mn(Ⅲ)/Co(Ⅱ) catalytic oxidative deacetylation. Further work on extending this catalytic oxidative reaction to the synthesis of some natural products is ongoing.
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| E-mail |
kooslaboffice@gmail.com |
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121st General Meeting of the KCS