121st General Meeting of the KCS

Type Oral Presentation
Area Oral Presentations of Young Scholars in Organic Division
Room No. Halla Hall B
Time THU 09:15-:
Code ORGN.O-2
Subject Divergent Catalytic Transformations of N-Sulfonyl-1,2,3-Triazoles into α-Aminoindanone and Isoquinolinone Derivatives
Authors Dajung Jung, Kyu Ree Lee1, Juhyun Kim2,*, Sang-gi Lee3,*
Department of Chemistry and Nano Science, Ewha Womans University, Korea
1Department of Chemistry and Nanoscience, Ewha Womans University, Korea
2Department of Chemistry, Gyeongsang National University, Korea
3Chemistry Department of Nano-Science, Ewha Womans University, Korea
Abstract N-sulfonyl-1,2,3-triazoles are the useful precursors inducing various derivations via metal carbene intermediates. During the rapid investigations of intramolecular reaction to various N-sulfonyl-1,2,3-triazoles , manufacturing them through thermal denitrogenative 1,2-hydride shift which generates N-sulfonyl ketenimine intermediates have become a new pathway toward the novel transformation of N-sulfonyl-1,2,3-triazoles. Therefore, controlling the formation of metal or free carbene intermediates under the catalytic conditions make divergent synthesis available. Herein, we developed intramolecular divergent catalytic reactions to control two pathways within introducing allyl alcohol group on phenyl ring of N-sulfonyl-1,2,3-triazoles affording isoquinolinone and 1-indanone derivatives according to two different catalytic reaction conditions.
E-mail thisisdajung@gmail.com