Self-folding cavitands are artificial receptors that are stabilized in their closed, concave conformation by non-covalent interactions. A new self-folding iminocavitand was designed and synthesized. The resorcin[4]arene-based cavitand bearing four 2-hydroxy benzamide moieties on the upper rim can fold into vase conformer by the four intramolecular C=O···H-O···H-N hydrogen bond sequence in the presence of suitable guests. Consequently a narrow and deep cavity is formed and stabilized, which was confirmed by NMR experiments. The synthesis and binding characteristics of this self-folding cavitand toward various guests will be presented.