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| Type |
Poster Presentation |
| Area |
Material Chemistry |
| Room No. |
Event Hall |
| Time |
4월 20일 (금요일) 11:00~12:30 |
| Code |
MAT.P-373 |
| Subject |
Monitoring the salicylate delivery of layered gadolinium hydroxide using green/blue luminescence change |
| Authors |
Hyunjin Jung, Hyunsub Kim, Song-ho Byeon*
Department of Applied Chemistry, Kyung Hee University, Korea
|
| Abstract |
Nanomaterial-based delivery system for releasing drug at a controlled rate for an extended period of time is often formed from a solid inner matrix material having solid particles of drug dispersed therethrough. Layered rare earth hydroxide family (LRHs) can also be a candidate for nanohybrids slowly releasing active ingredients because of its outstanding anion-exchange capacity between the hydroxocation layers where a large variety of inorganic/organic anions can be sheltered. Furthermore, the photoluminescence capability of LRHs is quite useful to monitor the inclusion/release behavior of drug ingredients by doping activator ions such as Ce3+, Eu3+, and Tb3+ into matrices. In the present work, a nonsteroidal anti-inflammatory agent, salicylic acid (2-hydroxybenzoic acid), was intercalated into the interlayer gallery of Tb3+ doped-layered gadolinium hydroxide (LGdH:Tb) via direct ion-exchange reaction. The characteristic 5D4 → 7FJ (J = 6, 5, and 4) green emissions of Tb3+, induced by the energy transfer from salicylate, provided a useful technique for “in-situ” monitoring the inclusion and release of salicylate. |
| E-mail |
jhj41100@naver.com |
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121st General Meeting of the KCS