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|
| Type |
Poster Presentation |
| Area |
Organic Chemistry |
| Room No. |
Event Hall |
| Time |
4월 19일 (목요일) 11:00~12:30 |
| Code |
ORGN.P-377 |
| Subject |
Palladium-catalyzed Tandem Homo-coupling of Terminal Alkynes and Hydroarylation of Nitropyrazoles |
| Authors |
Changhoon Shin, Jung Min Joo1,*
department of chemistry, Pusan National University, Korea
1Department of Chemistry, Pusan National University, Korea
|
| Abstract |
We have developed a Pd-catalyzed tandem reaction with terminal alkynes and nitropyrazoles. Although terminal alkynes have been considered to be challenging to use in C-H activation of (hetero)arenes because of facile dimerization, we achieved the tandem reaction forming the Pd-alkenyl complex to generate enynyl pyrazoles using diynes as a counterpart of pyrazoles. Depending on the equivalent of terminal alkynes and the type of oxidants, either the hydroarylation or the direct alkynylation occurred through different catalytic cycles. |
| E-mail |
hoooon264@gmail.com |
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121st General Meeting of the KCS