|
|
| Type |
Poster Presentation |
| Area |
Analytical Chemistry |
| Room No. |
Event Hall |
| Time |
4월 19일 (목요일) 11:00~12:30 |
| Code |
ANAL.P-242 |
| Subject |
Breath analysis by needle trap device(NTD) |
| Authors |
Ra-Yun Kim, In-Yong Eom1,*
Department of Chemistry, Daegu Catholic University, Korea
1Department of Life Chemistry, Daegu Catholic University, Korea
|
| Abstract |
Smoker’s exhaled breaths were analyzed by using a needle trap device (NTD) which is a miniaturized sorbent packed sampling device. The exhaled breath from a smoker was collected in a Tedlar bag and then volatile organic compounds (VOCs) in breath was sampled and concentrated through a NTD. The NTD was then inserted into a GC/MS injector to desorb thermally and transport them into a GC column. Well separated VOCs under such an optimum experimental conditions were identified tentatively using MS library and linear temperature programming retention index (LTPRI or Kovat index). To obtain optimized sampling conditions such as sampling flow rate, desorption temperature, sampling volume, etc., selected compounds in pure nitrogen gas was prepared in 0.5 ppm(nL/mL) level. Sampling temperature was also investigated. In addition, some artefact compounds released from a Tedlar bag can hinder the identification of VOCs from a breath sample so those artefacts are cleared identified in this study. This study shows that the NTD can be an excellent candidate to identify VOCs in breath analysis and further to diagnose a certain disease (for example Lung Cancer, Liver Disease, etc.) based on qualitative and quantitative information of VOCs in the future. |
| E-mail |
dori9529@naver.com |
|
121st General Meeting of the KCS