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Type |
Poster Presentation |
Area |
Organic Chemistry |
Room No. |
Event Hall |
Time |
4월 19일 (목요일) 11:00~12:30 |
Code |
ORGN.P-389 |
Subject |
Selective Debromination and α-Hydroxylation of α-Bromo Ketones Using Hantzsch ester as Photoreductants |
Authors |
Jun Kim, Youngmin You1,*, Eun Jin Cho* Department of Chemistry, Chung-Ang University, Korea 1Division of Chemical Advanced Materials, Ewha Womans University, Korea |
Abstract |
Two transformations initiated by photoinduced one-electron transfer to α-bromo ketones have been demonstrated. Hantzsch esters donate one electron to α-bromo ketones under photoirradiation, promoting reductive debromination. Subsequent reactions of the resulting radical species of the ketones with molecular oxygen and Hantzsch esters lead to α-hydroxylation or debromination, respectively. The relative dominance of the two pathways depends profoundly on the reaction conditions, including solvent, O2 levels, and the concentration of the Hantzsch esters. The synthetic protocols feature advantages because they require the environmentally benign sources, molecular oxygen and visible light. |
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E-mail |
motto18@nate.com |
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