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| Type |
Poster Presentation |
| Area |
Organic Chemistry |
| Room No. |
Event Hall |
| Time |
4월 19일 (목요일) 11:00~12:30 |
| Code |
ORGN.P-406 |
| Subject |
Fluorescent probe based on tetrapeptide receptor for ratiometric detection of As(III) in aqueous solution |
| Authors |
Semin Oh, Keun Hyeung Lee*
Department of Chemistry, Inha University, Korea
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| Abstract |
A fluorescent probe (1) was synthesized based on tetrapeptide receptor for arsenic species using solid phase synthesis. 1 showed selective ratiometric response to As(III) among 16 tested metal ions in aqueous buffered solution containing metal chelating agent, pyridine-2,6-dicarboxylic acid (PDCA). 1 exhibited a sensitive ratiometric response to As(III) and approximately, 1 equiv of As(III) was enough for the complete of the ratiometric responses. The detection limit for As(III) in ground water was measured to be 2.08 ppb, which is lower than the maximum allowable level of As(III) (10 ppb) in drinking water by EPA. Job's plot analysis, pH titration, and IR measurements (DLS measurents) revealed that 1 bound irreversibly with As(III) and the Cys residue of the peptide receptor play a critical role for this binding. |
| E-mail |
cvbn32@naver.com |
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121st General Meeting of the KCS