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|
| Type |
Poster Presentation |
| Area |
Analytical Chemistry |
| Room No. |
Event Hall |
| Time |
4월 19일 (목요일) 11:00~12:30 |
| Code |
ANAL.P-251 |
| Subject |
Fabrication and application of cell-based microfluidic chip for eye-irritation test of compounds |
| Authors |
Sujin Cho, Tian Tian, Seog Woo Rhee*
Department of Chemistry, Kongju National University, Korea
|
| Abstract |
In this presentation, we will describe the development and application of cell-based microfluidic chip to perform eye-irritation test. The device was fabricated with a milti-compartment diffusion channels for culture of cells. HUVEC and fibroblast cells were cultured in the milti-compartment channels and the solutions of test compounds were injected to the inlet of the channel and diffused through the connected microfluidic channels. The viability of cells in each compartment was monitored by an optical microscope. Several types of cosmetic materials were tested with test systems, and the IS (irritation score) values were evaluated and compared with those of other test methods to validate the test system developed in this work. |
| E-mail |
jisanrhee@kongju.ac.kr |
|
121st General Meeting of the KCS