|
Type |
Symposium |
Area |
Functional Nanocomposite Materials |
Room No. |
Samda Hall A |
Time |
FRI 15:10-: |
Code |
MAT3-3 |
Subject |
Biomimetic surface functionalization for biointerface engineering |
Authors |
Seonki Hong Department of Emerging Materials Science, Daegu Gyeongbuk Institute of Science & Technology, Korea |
Abstract |
Biointerface is the area of contact between 1) biomacromolecules, cells, biological tissues or living organism and 2) other biomaterials or synthetic organic/inorganic materials. Engineering of molecular interactions/recognitions occurred at the biointerface is essential in designing a novel biochip for in vitro bioassays. Plastics are emerging as substrates for lab-on-a-chip microfluidics as they often have ideal material properties. For example, they are transparent to allow optical measurements, rigid but not fragile, and solvent-resistant. Furthermore, plastic devices can be molded into complex shapes, and mass-produced at low cost. Plastics, however, are challenging materials for biological activation; the material surface is highly hydrophobic and inherently lacks chemical functional groups (in particular, hydrocarbon-based plastics like PE, PP, and PS). In this seminar, I will introduce the biomimetic strategies to develop robust and generalizable surface chemistries, in particular for plastics, to generate bioactive surface for biomolecular interactions/recognitions. Biointerface engineering of plastic medical devices would catalyze the more widespread use of cost-effective plastic in biosensing and other biomedical applications. |
E-mail |
seonkihong@dgist.ac.kr |
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