121st General Meeting of the KCS

Type Symposium
Area Functional Nanocomposite Materials
Room No. Samda Hall A
Time FRI 15:10-:
Code MAT3-3
Subject Biomimetic surface functionalization for biointerface engineering
Authors Seonki Hong
Department of Emerging Materials Science, Daegu Gyeongbuk Institute of Science & Technology, Korea
Abstract Biointerface is the area of contact between 1) biomacromolecules, cells, biological tissues or living organism and 2) other biomaterials or synthetic organic/inorganic materials. Engineering of molecular interactions/recognitions occurred at the biointerface is essential in designing a novel biochip for in vitro bioassays. Plastics are emerging as substrates for lab-on-a-chip microfluidics as they often have ideal material properties. For example, they are transparent to allow optical measurements, rigid but not fragile, and solvent-resistant. Furthermore, plastic devices can be molded into complex shapes, and mass-produced at low cost. Plastics, however, are challenging materials for biological activation; the material surface is highly hydrophobic and inherently lacks chemical functional groups (in particular, hydrocarbon-based plastics like PE, PP, and PS). In this seminar, I will introduce the biomimetic strategies to develop robust and generalizable surface chemistries, in particular for plastics, to generate bioactive surface for biomolecular interactions/recognitions. Biointerface engineering of plastic medical devices would catalyze the more widespread use of cost-effective plastic in biosensing and other biomedical applications.
E-mail seonkihong@dgist.ac.kr