121st General Meeting of the KCS

Type Symposium
Area Recent Advances in Analytical Chemistry II: Analysis of Environmental Pollutants
Room No. Room 201A
Time FRI 15:40-:
Code ANAL2-4
Subject Cucurbituril Functionalized Organic Transistor Sensors for Drug Detection and Environmental Monitoring
Authors Ilha Hwang
Center for Self-assembly and Complexity, Institute for Basic Science, Korea
Abstract Sensors based on organic field-effect transistors (OFETs) show great promise as chemical or biological sensors because they have a number of advantages, including high sensitivity, low cost, simple fabrication, fast response, and flexible applications. However, pristine OFET-based sensors typically exhibit low selectivity because of the lack of recognition units. Therefore, highly selective detection with OFET based sensors often requires chemical modification of specific receptors on the electroactive layer to selectively capture target analytes. Cucurbit[n]urils (CB[n]s), synthetic macrocyclic host molecules with n glycol units, have unique recognition properties and can be used for the detection of various analytes including amphetamine-type stimulants and endocrine disruptors. Here, a strategy that synergistically combines the selectivity of host-guest chemistry of CBs and the sensitivity of OFETs will be presneted. Furthermore, a portable and miniaturized sensor with a wireless communication system that could be utilized for rapid point-of-use detection of analyte will be demonstrated. These works provide a low-cost, simple, and viable methodology for the fabrication of highly sensitive and selective sensors, and may open an avenue to new opportunities to replace current detection methods.
E-mail ihwang1@ibs.re.kr