Taxamairin A and B have been isolated from the bark of Taxus mairei in 1987. An initial survey of Taxamairin A and B identified inhibitory activity against hepatoma (liver tumor) cells. We have developed benzene skeleton synthesis for taxamairin B in our laboratory. And now, We are develop the synthesis more efficient, more economical. The Taxamairin B will be synthesized by a facile route, which employed the Au or Pt-catalyzed cyclization of an enynal that was easily prepared in a convergent manner.