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| Type |
Poster Presentation |
| Area |
Medicinal Chemistry |
| Room No. |
Event Hall |
| Time |
4월 19일 (목요일) 11:00~12:30 |
| Code |
MEDI.P-619 |
| Subject |
Biologically active compounds from Mucunae Caulis |
| Authors |
Ji Yun Lee*, MINJI KIM, Bong Ho Lee1,*, Byong Wook Choi2,*
Hanbat National University, Korea
1Division of Applied Chemistry & Biological Enginee, Hanbat National University, Korea
2Department of Chemical & Biological Engineering, Hanbat National University, Korea
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| Abstract |
In our continuing search for anti-oxidative and anti-cholinesterase compounds from oriental medicinal plant, Mucunae Caulis was examined and here we report the progress on the purification and structural determination of anti-cholinesterase compounds. From the 100% methanol extract of M. Caulis (500g), solvent partition fractions were prepared by using n-hexane, chloroform, butanol, water. Among them chloroform fraction showed strong anti-oxidation, *BuChE inhibition, and tyrosinase inhibitory activities. Bioactive compounds were purified through a series of various chromatographic methods. Biological activities and structure determination of the bioactive compounds will be presented.
*BuChE : butyrylcholinesterase
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| E-mail |
ruby_zz@naver.com |
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121st General Meeting of the KCS