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| Type |
Poster Presentation |
| Area |
Physical Chemistry |
| Room No. |
Event Hall |
| Time |
4월 20일 (금요일) 11:00~12:30 |
| Code |
PHYS.P-179 |
| Subject |
Photodissociation Dynamics of Nitric Oxide From Roussin’s Red Ester Probed by Time-Resolved Infrared Spectroscopy |
| Authors |
hojeong yoon, Seongchul Park, Manho Lim*
Department of Chemistry, Pusan National University, Korea
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| Abstract |
Roussin`s red ester (RRE), [Fe2(μ-RS)2(NO)4] was discovered for a long time ago and recent interest in NO donor has increased study of RRE as a NO donor in biology and medicine. RRE has been an important NO donor due to a relatively low toxicity, good stability, and simple synthesis. Photoexcitation of RRE produces NO that can be utilized as the medical purposes. Various thiol molecules were used to synthesize RRE. Stability, quantum yield for NO generation, and solubility of RRE are related to the thiol molecule used. Thiol with a polar group is advantageous for biological usage which requires water solubility. Since cysteine (CysSH) is a water soluble natural amino acid, it was used in synthesizing RRE for a biological application. CysSH-containing RRE, [Fe2(μ-CysS)2(NO)4] (Cys-RRE) is thermally stable for about a day at room temperature. Here, photodissociation dynamics of NO from Cys-RRE in water was investigated by probing the N−O stretching mode. We were able to identify reaction intermediates in the photolysis and establish subsequent reactions of the intermediates as well as photodissociated NO with nascent photoproducts. |
| E-mail |
yun6793@naver.com |
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121st General Meeting of the KCS