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| Type |
Poster Presentation |
| Area |
Physical Chemistry |
| Room No. |
Event Hall |
| Time |
4월 20일 (금요일) 11:00~12:30 |
| Code |
PHYS.P-181 |
| Subject |
Study of Erythrocyte Membrane Using Combined AFM-TIRFM Technique |
| Authors |
KWANGDON BAE, Doo Wan Boo*
Department of Chemistry, Yonsei University, Korea
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| Abstract |
The erythrocyte membrane skeleton is a hexagonal meshwork of spectrin, protein 4.1R, actin complex and ankyrin complex. Because of its unique structural composition, the erythrocyte is remarkably deformable and stable. However, the precise structural information of skeleton has not yet been discovered as well as the distribution of lipid/protein. For this reason and for their relatively simple structure and convenience of isolation, erythrocyte has been extensively studied over the years.
We used a combined Atomic Force Microscopy (AFM) and Total Internal Reflection Fluorescence Microscopy (TIRFM) technique to investigate the morphology, distribution and dynamics of erythrocyte membrane. We first immobilized the erythrocyte on modified glass surfaces, then characterized the size and locations of specific membrane protein/lipid by AFM-TIRFM technique.
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| E-mail |
mypetiset@naver.com |
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121st General Meeting of the KCS