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|
| Type |
Poster Presentation |
| Area |
Material Chemistry |
| Room No. |
Event Hall |
| Time |
4월 20일 (금요일) 11:00~12:30 |
| Code |
MAT.P-486 |
| Subject |
Enhanced Water dispersibility of Carbon Nitride Nanodots Using PEGylation and Bioimaging Application |
| Authors |
Sunghee Park, Sungjin Park*
Department of Chemistry, Inha University, Korea
|
| Abstract |
In this work, we incorporated short chain polyethylene glycol (PEG) groups onto carbon nitride network by the simple N-alkylation of hexaethylene glycolic mesylate with nucleophilic nitrogen atoms on oxidized carbon nitride (OCN). Fluorescent materials in the cells needs well water dispersibility, and biocompatible imaging probes The PEGylated OCN (PEG-OCN) was well dispersed in water as nanodots with ~30 nm of lateral dimension and 0.5 – 1.2 nm of thickness, and showed strong photoluminescence in the visible region. Cell viability testing confirmed that these “heavy metal free” organic nanodots were highly biocompatible and noncytotoxic. In particular, the developed nanodots could provide clear confocal images of RAW 264.7 cells without weakening cell activity and displaying any aggregation at a range of concentrations (25 – 100 µg/mL) with bright green-emission in the cytoplasm. |
| E-mail |
sunghui0928@gmail.com |
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121st General Meeting of the KCS