|
Type |
Poster Presentation |
Area |
Medicinal Chemistry |
Room No. |
Event Hall |
Time |
4월 19일 (목요일) 11:00~12:30 |
Code |
MEDI.P-643 |
Subject |
Efficient and Rapid synthesis of 3,4 unsubstituted isoqunolin-1(2H)-one under Mild conditions |
Authors |
Akshay Takwale, Yeong Uk Jeon1, Jong Yeon Hwang2,* University of Science & Technology, India 1pharmacy, Sungkyunkwan University, Korea 2Center for Medicinal Chemistry, Korea Research Institute of Chemical Technology, Korea |
Abstract |
We have Depicted the simple and efficient synthesis of 3,4 unsubstituted isoqunolin-1(2H)-one derivatives. Initiating with the coupling of vinyl ethers with different amines followed by rapid intramolecular cyclisation involving Acidic conditions at room temperature. The product thus obtained is further involved in Suzuki coupling reaction in some of our derivatives. |
E-mail |
dtakshay@krict.re.kr |
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