121st General Meeting of the KCS

Type Poster Presentation
Area Medicinal Chemistry
Room No. Event Hall
Time 4월 19일 (목요일) 11:00~12:30
Code MEDI.P-643
Subject Efficient and Rapid synthesis of 3,4 unsubstituted isoqunolin-1(2H)-one under Mild conditions
Authors Akshay Takwale, Yeong Uk Jeon1, Jong Yeon Hwang2,*
University of Science & Technology, India
1pharmacy, Sungkyunkwan University, Korea
2Center for Medicinal Chemistry, Korea Research Institute of Chemical Technology, Korea
Abstract We have Depicted the simple and efficient synthesis of 3,4 unsubstituted isoqunolin-1(2H)-one derivatives. Initiating with the coupling of vinyl ethers with different amines followed by rapid intramolecular cyclisation involving Acidic conditions at room temperature. The product thus obtained is further involved in Suzuki coupling reaction in some of our derivatives.
E-mail dtakshay@krict.re.kr