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| Type |
Poster Presentation |
| Area |
Organic Chemistry |
| Room No. |
Event Hall |
| Time |
4월 19일 (목요일) 11:00~12:30 |
| Code |
ORGN.P-512 |
| Subject |
Efficient Synthesis of 1-Sulfonyl and 1-Sulfamoyl-1,2,3-Triaozoles
Employing Continuous Flow Microreactor
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| Authors |
Yong-Ju Kwon, Wonsuk Kim1,*
Department of Chemistry and Nano Science, Ewha Womans University, Korea
1Chemistry Department of Nano-Science, Ewha Womans University, Korea
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| Abstract |
1-Sulfonyl-1,2,3-triazoles are useful compounds which can be serve as a precursor of reactive azavinyl carbenes. Because of their weak N1-N2 bond, they can easily transform to diazoimines through ring-chain tautomerization and it leads to subsequent conversion to the transition metal-carbene complexes. Thus, many different batch-type methods for the preparation of 1-Sulfonyl-1,2,3-triazoles have been developed. However, most batch-type conditions require long reaction time. Herein, we report an efficient method for the synthesis of 1-sulfonyl- and 1-sulfamoyl-1,2,3-triazoles employing continuous flow microreactor in s short residence time. In addition, we generated N-allylated (Z)-amino vinyl carboxylates with α-imino Rh(Ⅱ) carbenoids derived from triazoles by using an flow synthesis system.
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| E-mail |
rdjwkd@naver.com |
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121st General Meeting of the KCS