|
Type |
Poster Presentation |
Area |
Physical Chemistry |
Room No. |
Event Hall |
Time |
4월 20일 (금요일) 11:00~12:30 |
Code |
PHYS.P-213 |
Subject |
Hetero-spectral 2D correlation analysis of the denaturation process of α-lactalbumin by fluorescence and IR spectroscopies
|
Authors |
YUJEONG PARK, Yeonju Park, Young Mee Jung* Department of Chemistry, Kangwon National University, Korea |
Abstract |
It is important to understand the denaturation mechanism of protein because it provides fundamental knowledge in the study of disease caused by protein denaturation. A representative whey protein, α-lactalbumin undergoes an intermediate state at a specific pH during denaturation process. In this study, the pH-induced denaturation process of α-lactalbumin was explored by fluorescence and IR spectroscopies. Principal component analysis (PCA) and hetero-spectral two-dimensional correlation spectroscopy (2DCOS) were used to understand denaturation mechanism of α-lactalbumin. Details on the results of pH-induced fluorescence and IR spectral changes of α-lactalbumin will be discussed in this presentation. |
E-mail |
po01266@naver.com |
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